DHADHA Medical Laboratory Technologist Exam

    Immunology and Serology questions for the DHA lab exam.

    Immunology and Serology covers innate and adaptive immunity, antibody structure and function, antigen-antibody reactions and the serological tests used to diagnose infections and autoimmune disease. Candidates for the DHA lab exam should understand the principles of methods such as ELISA, agglutination and immunofluorescence and interpret common serology patterns.

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    389

    immunology and serology practice questions

    8%
    of the exam
    8
    subtopics
    Oct 2026
    updated

    Inside this topic.

    The subtopics our immunology and serology questions cover.

    • Serologic Techniques
    • Immunodeficiency
    • Immunoglobulins
    • Antibodies
    • Autoimmune Diseases
    • Virology
    • Infectious Serology
    • Tumor Markers

    Key facts to remember.

    High-yield immunology and serology points to revise before the exam.

    1. 1

      IgM is the first antibody produced in a primary immune response and is a pentamer; IgG is the only class that crosses the placenta.

    2. 2

      In hepatitis B, HBsAg indicates current infection, anti-HBs indicates immunity and IgM anti-HBc indicates recent (acute) infection.

    3. 3

      The prozone effect is a false-negative reaction caused by antibody excess; testing serial dilutions of the serum reveals the true result.

    4. 4

      Antinuclear antibodies are screened by indirect immunofluorescence on HEp-2 cells; anti-dsDNA and anti-Sm antibodies are highly specific for SLE.

    5. 5

      VDRL and RPR are non-treponemal screening tests for syphilis, and reactive results are confirmed with treponemal tests such as TPPA or FTA-ABS.

    Sample questions with answers.

    10 practice questions for the DHA Medical Laboratory Technologist & Technician Licensing Examination - Dubai UAE (Immunology and Serology). Pick an answer to see if you're right, with a full explanation.

    1. Question 1

      Which disease is associated with anti-TSH receptor antibodies?

    2. Question 2

      Which immunoglobulin is first produced in an acute infection?

    3. Question 3

      Which test uses radioisotopes for detection?

    4. Question 4

      Which hepatitis marker indicates acute hepatitis B infection?

    5. Question 5

      Which immunoglobulin is dimeric and contains a secretory component?

    6. Question 6

      Which test is MOST specific for syphilis?

    7. Question 7

      Which immunoglobulin is found on the surface of naïve B cells?

    8. Question 8

      Which immunoglobulin is most abundant in external secretions?

    9. Question 9

      Which complement component is responsible for opsonization?

    10. Question 10

      A negative serology early in infection is best explained by?

    Questions, answered

    Read each marker in turn: HBsAg for presence of the virus, anti-HBc for past or current infection (IgM for recent infection) and anti-HBs for immunity. Anti-HBs alone with a negative anti-HBc indicates vaccination, while anti-HBs with anti-HBc indicates resolved natural infection. Writing out a small table of the common patterns is a quick way to revise.

    Direct immunofluorescence detects antigen in a tissue sample using a labeled antibody, whereas indirect immunofluorescence detects antibody in the patient's serum using a labeled anti-human globulin. Similarly, agglutination involves particulate antigens such as cells or latex beads, while precipitation involves soluble antigens. Learn the principle behind each method rather than just its name.

    Ready to practise immunology and serology?

    All 389 immunology and serology questions, with explanations and a readiness score for this topic.